It strikes me that a good way to structure a seminar is to choose one important book and, along with it, read essentially everything the author cites. This method would obviously work mainly with modern texts, but it could work equally in theology and continental philosophy (the disciplines between which I am “interdisciplined”). In discussion with our very own JD, I once proposed a multi-semester seminar based on Pannenberg’s Anthropology in Theological Perspective, after which everyone involved would be tied for the most educated person alive. Milbank’s Theology and Social Theory would also allow for a similar expansiveness and would allow the students to gauge his polemic. In continental philosophy, Agamben would be an especially valuable target for such treatment, not only because he is reading such fascinating texts most of the time (what would be better than a course based on The Open?), but also because you would get a sense of how rushed his readings of many figures, including those most important to him*, can be.
The Agamben and Milbank examples would also serve a kind of meta-pedagogical purpose beyond simply providing a broad reading list and a detailed example of how to go about assessing a major work — it would attract the kind of student who follows the “cool” contemporary stuff and tends toward a kind of presentism (i.e., the kind of student I was and in many ways still am), but for the purpose of disillusioning them a bit and broadening their horizon.
[*Random free dissertation topic: Agamben and Heidegger on Aristotle.]